But the process can be time-consuming and labor intensive, with an estimated 1,500-3,000 article reviews a week for large global biopharmas. For smaller biopharmas, this process may be outsourced, creating data and operational silos. Common challenges include:<\/p>\n
- \n
- Scaling high volumes of literature review from a wide range of sources<\/li>\n
- Manual data capture across systems when ICSRs and signals are detected<\/li>\n
- Misalignment or missed data between in-house teams and outsourcing partners who are responsible for a portion of the process (e.g., case processing vs. literature review)<\/li>\n<\/ul>\n
Inefficient and manual literature review processes create compliance and patient safety risks.<\/p>\n
Streamline case intake for faster ICSR reporting<\/h2>\n
Safety teams can streamline the literature review process by enabling bulk literature article intake, from sources like PubMed, to greatly reduce administrative overhead manually aggregating articles. When reviewers identify ICSRs, integrating the literature review process with your safety system allows them to seamlessly create a safety inbox item for case processing with just a few clicks. <\/p>\n
Seamless literature review and case processing:<\/p>\n
- \n
- Simplifies the literature review to case intake process<\/li>\n
- Enables seamless transfer of literature data to the safety inbox item<\/li>\n
- Supports traceability of ICSRs back to the literature source<\/li>\n
- Reduces manual data entry and reconciliation<\/li>\n<\/ul>\n
Learn how Veeva SafetyDocs<\/a> drives operational efficiency and improves patient safety.<\/p>\n
![\"\"](\"https:\/\/www.veeva.com\/wp-content\/uploads\/2025\/10\/resource-tile-safety-demo-literature-680x480-1.png\")
<\/p>\n\nDemo: Faster Literature Review to Case Intake <\/h2>\n
See how to manage literature reviews<\/a> more efficiently and identify possible ICSRs or safety signals faster with Veeva SafetyDocs.<\/p>\n<\/div>\n
<\/div>\n![\"\"](\"https:\/\/www.veeva.com\/wp-content\/uploads\/2025\/10\/safety-newsletter-NIH-NLM-680x480-1.png\")
<\/p>\n\nImpact of literature reports on drug safety signals<\/h2>\n
Literature review is a significant source of individual safety case reports (ICSRs), according to a 2020 study by the NIH<\/a>.<\/p>\n<\/div>\n